Researchers have long sought a factor that can trigger the brain’s ability to learn – and perhaps recapture the “sponge-like” quality of childhood. Neuroscientists at Children’s Hospital Boston report that they’ve identified such a factor, a protein called Otx 2. Otx2 helps a key type of cell in the cortex to mature, initiating a critical period–a window of heightened brain plasticity, when the brain can readily make new connections.
And where does this protein come from? Interestingly enough, it is developed in the cornea. Basically, when the eye opens and is functional, it tells the brain to start receiving data and learning.
“The eye is telling the brain when to become plastic, rather than the brain developing on its own clock,” says Hensch, who is also a professor at Harvard Medical School and at Harvard University’s Department of Molecular & Cellular Biology. In essence, the eye is telling the brain, “The eyes are ready and seeing properly — you can rewire now.”
In a Spongebob Squarepants cartoon, Spongebob gets up one morning and thinks he’ll create a fantastic dessert for himself. Unfortunately, his choice of ingredients cause him to have horrific halitosis (bad breath). Spongebob proceeds to go outside, where he meets several people, all of whom scream and run away from him as soon as he opens his mouth and says, “Hello.”